Non-invasive prenatal diagnosis based on cell-fre fetal DNA: update

Authors

  • Walter Ricardo Ventura Laveriano Past Fellow Harris Birthright Research Centre for Fetal Medicine, King’s College Hospital, Londres, Reino Unido; Unidad de Medicina Fetal, Departamento de Obstetricia y Perinatología, Instituto Nacional Materno Perinatal, Lima, Perú

DOI:

https://doi.org/10.31403/rpgo.v60i141

Abstract

The discovery of cell free fetal DNA (cff-DNA) in maternal circulation has profoundly changed the clinical practice of Obstetrics and knocked down an old paradigm in prenatal diagnosis. Over the past five years screening for chromosomal abnormalities has moved from one with a high false positive rate into another more effective and at lower false positive rate. Undoubtedly, this test is the best effective screening tool in Obstetrics.

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Published

2014-10-12

Issue

Section

Artículos de Revisión